As It Moves Out of the Lab, CRISPR Brings Tough Questions into the Clinic

October 9, 2018

(STAT News) – The genome editing technology CRISPR has evolved from the darling of research labs around the world — enabling new types of experiments in a much more efficient way — to the great hope for unlocking cures for inherited diseases. But as scientists ready CRISPR-based therapies for clinical trials, how can they reduce the chances that they might edit parts of the genome that weren’t targeted? And how can they get CRISPR editing complexes to the targeted cells to make the necessary fixes to treat or cure a disease?

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