Chinese Scientists Fix Genetic Disorder in Cloned Human Embryos

October 3, 2017

(Nature) – A team in China has taken a new approach to fixing disease genes in human embryos. The researchers created cloned embryos with a genetic mutation for a potentially fatal blood disorder, and then precisely corrected the DNA to show how the condition might be prevented at the earliest stages of development. The report, published on 23 September in Protein & Cell is the latest in a series of experiments to edit genes in human embryos. And it employs an impressive series of innovations, scientists say. Rather than replacing entire sections of genes, the team, led by Junjiu Huang at Sun Yat-sen University in Guangzhou, China, tweaked individual DNA letters, or bases, using a precision gene-editing technology developed in the United States.

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